Aplastic Anaemia

Article published on 29th July 2008

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Over the next few articles we'll be looking at some more of the conditions and illnesses that are usually covered Critical Illness Insurance (CII), starting in this article with Aplastic Anaemia,

Anaemia is the condition of having a reduced red cell, or haemoglobin, concentration in the blood. Aplastic is form of anaemia is caused by bone marrow that suffers from 'aplasia' that renders it unable to produce enough new to replenish blood cells.

Where 'normal' anaemia creates a low red blood cell count, aplastic anaemia causes lower-than-healthy counts of all three blood cell types: red and white blood cells and platelets.

In many cases, the cause of aplastic anaemia is exceedingly difficult to determine, but it is sometimes connected to an exposure to substances such as radiation and benzene. The use of certain drugs like chloramphenicol, carbamazapine, phenytoin, felbamate, quinine, and phenylbutazone.

Even so, the connection are difficult to establish, as, for example, chloramphenicol treatment leads to aplasia in less than 1 in 40,000 treatment courses. Although aplastic anaemia is purported to present in nearly 2% of patients with acute viral hepatitus.

If left untreated, aplastic Anaemia can leads to a rapid death, typically within 6 months of diagnosis, although there are occasional milder cases that resolve on their own.

Sources:

http://www.aamds.org/aplastic/

http://www.nlm.nih.gov/medlineplus/ency/article/000554.htm

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